Make sure that you assign a dedicated area solely for work purposes. It can be extremely tempting to have a relaxing working day from bed, however, even with the most comfortable bed frame, this can be damaging for your posture and spinal health as most bed frames have not been designed for extensive working hours.
Create a desk area that will be both comfortable and provide enough working space. Placing your desk or table close to a window will prevent you from feeling sleepy. Other ways to keep you awake are; incorporating items in that area which will inspire you such as flowers or photographs.
Last of all, take time to rest - you deserve it!